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Bubonic plague
The most famous pandemic around the world was called Black Death and claimed from 75 to 200 million people. This disease mainly affected Europe, Asia and Africa in the middle of the XIV century. In some regions and provinces, mortality was up to 90%. The plague was manifested by numerous bleeding ulcers in the body (the so-called «buboes») and high fever. Naturally, medieval treatment methods in the form of applying herbs and snake skin to wounds did not give the desired result, so the fight against a pandemic was difficult and protracted.
